产品货号:
Z24477
中文名称:
PPPDE1/PNAS4/DESI2抗体
英文名称:
Anti-PPPDE1/PNAS4/DESI2 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PPPDE1/PNAS4/DESI2 Antibody |
指标别名 | DESI2,Desumoylating isopeptidase 2,FAM152A,PNAS 4,PPPDE1 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB |
基因名称 | DESI2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | PNAS4 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human PNAS4.The immunogen is located within the last 50 amino acids of PNAS4. |
计算分子量 | 21kDa |
成分 | PNAS4 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | PNAS4 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | PNAS4 is a highly conserved protein that shares high homology from plants to animals.It was initially identified as a putative apoptosis-related protein in the human acute promyelocytic leukemia cell line NB4.PNAS4 is activated during the early response to DNA damage and can inhibit proliferation via apoptosis when overexpressed in some tumor cells such as U2OS,SKOV3,and A549.PNAS4 inhibits tumor cell proliferation through the following mechanisms:(i) overexpression of PNAS4 causes S phase arrest by regulating the expression of cell cycle-related proteins and (ii) PNAS4 induces apoptosis through the mitochondrial apoptosis pathway.Recent evidence has shown that PNAS4 may be involved in the genesis of some cancers and could be a potential candidate for lung cancer therapy alone or in combination with gemcitabine.At least two isoforms of PNAS4 are known to exist. |
Uniprot ID | Q9BSY9 |
基因名全称 | Desumoylating isopeptidase 2 |
蛋白名全称 | Desumoylating isopeptidase 2 |
推荐稀释比 | PNAS4 antibody can be used for detection of PNAS4 by Western blot at 1 ~ 2μg/mL.Antibody validated:Western Blot in mouse samples.All other applications and species not yet tested. |
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